A role for WRN in telomere-based DNA damage responses

Telomeres cap the ends of eukaryotic chromosomes and prevent them from being recognized as DNA breaks. We have shown that certain DNA damage responses induced during senescence and, at times of telomere uncapping, also can be induced by treatment of cells with small DNA oligonucleotides homologous t...

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Main Authors: Eller, Mark S., Liao, Xiaodong, Liu, SuiYang, Hanna, Kendra, Bäckvall, Helena, Opresko, Patricia L., Bohr, Vilhelm A., Gilchrest, Barbara A.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2006
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1586178/
https://ncbi.nlm.nih.gov/pubmed/17015833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607332103
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