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Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops

Werner syndrome is an inherited human progeriod syndrome caused by mutations in the gene encoding the Werner Syndrome protein, WRN. It has both 3'-5' DNA helicase and exonuclease activities, and is suggested to have roles in many aspects of DNA metabolism, including DNA repair and telomere...

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Detalhes bibliográficos
Main Authors: Kusumoto-Matsuo, Rika, Opresko, Patricia L., Ramsden, Dale, Tahara, Hidetoshi, Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898018/
https://ncbi.nlm.nih.gov/pubmed/20519774
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