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Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1
Telomeres are nucleoprotein complexes at the ends of linear chromosomes in eukaryotes, and are essential in preventing chromosome termini from being recognized as broken DNA ends. Telomere shortening has been linked to cellular senescence and human aging, with oxidative stress as a major contributin...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3010491/ https://ncbi.nlm.nih.gov/pubmed/20951653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.09.008 |
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