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Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1

Telomeres are nucleoprotein complexes at the ends of linear chromosomes in eukaryotes, and are essential in preventing chromosome termini from being recognized as broken DNA ends. Telomere shortening has been linked to cellular senescence and human aging, with oxidative stress as a major contributin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rhee, David B., Ghosh, Avik, Lu, Jian, Bohr, Vilhelm A., Liu, Yie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010491/
https://ncbi.nlm.nih.gov/pubmed/20951653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.09.008
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