Amylin Selectively Signals Onto POMC Neurons in the Arcuate Nucleus of the Hypothalamus

Amylin phosphorylates ERK (p-ERK) in the area postrema to reduce eating and synergizes with leptin to phosphorylate STAT3 in the arcuate (ARC) and ventromedial (VMN) hypothalamic nuclei to reduce food intake and body weight. The current studies assessed potential amylin and amylin-leptin ARC/VMN int...

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Bibliografske podrobnosti
izdano v:Diabetes
Main Authors: Lutz, Thomas A., Coester, Bernd, Whiting, Lynda, Dunn-Meynell, Ambrose A., Boyle, Christina N., Bouret, Sebastien G., Levin, Barry E., Le Foll, Christelle
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2018
Teme:
Metabolism
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910000/
https://ncbi.nlm.nih.gov/pubmed/29467172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-1347
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