Amylin Selectively Signals Onto POMC Neurons in the Arcuate Nucleus of the Hypothalamus

Amylin phosphorylates ERK (p-ERK) in the area postrema to reduce eating and synergizes with leptin to phosphorylate STAT3 in the arcuate (ARC) and ventromedial (VMN) hypothalamic nuclei to reduce food intake and body weight. The current studies assessed potential amylin and amylin-leptin ARC/VMN int...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Lutz, Thomas A., Coester, Bernd, Whiting, Lynda, Dunn-Meynell, Ambrose A., Boyle, Christina N., Bouret, Sebastien G., Levin, Barry E., Le Foll, Christelle
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2018
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910000/
https://ncbi.nlm.nih.gov/pubmed/29467172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-1347
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