Amylin-Induced Central IL-6 Production Enhances Ventromedial Hypothalamic Leptin Signaling

Amylin acts acutely via the area postrema to reduce food intake and body weight, but it also interacts with leptin over longer periods of time, possibly via the ventromedial hypothalamus (VMH), to increase leptin signaling and phosphorylation of STAT3. We postulated that amylin enhances VMH leptin s...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Le Foll, Christelle, Johnson, Miranda D., Dunn-Meynell, Ambrose A., Boyle, Christina N., Lutz, Thomas A., Levin, Barry E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2015
Assuntos:
Obesity Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407855/
https://ncbi.nlm.nih.gov/pubmed/25409701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0645
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