Amylin-Induced Central IL-6 Production Enhances Ventromedial Hypothalamic Leptin Signaling

Amylin acts acutely via the area postrema to reduce food intake and body weight, but it also interacts with leptin over longer periods of time, possibly via the ventromedial hypothalamus (VMH), to increase leptin signaling and phosphorylation of STAT3. We postulated that amylin enhances VMH leptin s...

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Vydáno v:Diabetes
Hlavní autoři: Le Foll, Christelle, Johnson, Miranda D., Dunn-Meynell, Ambrose A., Boyle, Christina N., Lutz, Thomas A., Levin, Barry E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2015
Témata:
Obesity Studies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407855/
https://ncbi.nlm.nih.gov/pubmed/25409701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0645
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