Tanycytic VEGF-A Boosts Blood-Hypothalamus Barrier Plasticity and Access of Metabolic Signals to the Arcuate Nucleus in Response to Fasting

The delivery of blood-borne molecules conveying metabolic information to neural networks that regulate energy homeostasis is restricted by brain barriers. The fenestrated endothelium of median eminence microvessels and tight junctions between tanycytes together compose one of these. Here, we show th...

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Autori principali: Langlet, Fanny, Levin, Barry E., Luquet, Serge, Mazzone, Massimiliano, Messina, Andrea, Dunn-Meynell, Ambrose A., Balland, Eglantine, Lacombe, Amelie, Mazur, Daniele, Carmeliet, Peter, Bouret, Sebastien G., Prevot, Vincent, Dehouck, Bénédicte
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695242/
https://ncbi.nlm.nih.gov/pubmed/23562080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.03.004
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