Mechanisms of tolvaptan-induced toxicity in HepG2 cells()

Tolvaptan, a vasopressin receptor 2 antagonist used to treat hyponatremia, has recently been reported to be associated with an increased risk of liver injury. In this study, we explored the underlying mechanisms of hepatotoxicity of tolvaptan using human HepG2 cells. Tolvaptan inhibited cell growth...

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Detaylı Bibliyografya
Yayımlandı:Biochem Pharmacol
Asıl Yazarlar: Wu, Yuanfeng, Beland, Frederick A., Chen, Si, Liu, Fang, Guo, Lei, Fang, Jia-Long
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894093/
https://ncbi.nlm.nih.gov/pubmed/25858412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.03.015
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