Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity

Hepatic metabolism catalyzed by the cytochrome P450 (CYP) superfamily affects liver toxicity associated with exposures to natural compounds and xenobiotic agents. Previously we generated a battery of HepG2-derived stable cell lines that individually express 14 CYPs (1A1, 1A2, 1B1, 2A6, 2B6, 2C8, 2C9...

Full description

Saved in:
Bibliographic Details
Published in:J Environ Sci Health C Toxicol Carcinog
Main Authors: Chen, Si, Wu, Qiangen, Li, Xilin, Li, Dongying, Mei, Nan, Ning, Baitang, Puig, Montserrat, Ren, Zhen, Tolleson, William H., Guo, Lei
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931144/
https://ncbi.nlm.nih.gov/pubmed/33576714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/26896583.2021.1880242
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items