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Activation of the Nrf2 signaling pathway in usnic acid-induced toxicity in HepG2 cells
Many usnic acid-containing dietary supplements have been marketed as weight loss agents, although severe hepatotoxicity and acute liver failure have been associated with their overuse. Our previous mechanistic studies revealed that autophagy, disturbance of calcium homeostasis, and ER stress are inv...
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Publicado no: | Arch Toxicol |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5727582/ https://ncbi.nlm.nih.gov/pubmed/27369375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1775-y |
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