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The role of hepatic cytochrome P450s in the cytotoxicity of dronedarone

Dronedarone is used to treat patients with cardiac arrhythmias and has been reported to be associated with liver injury. Our previous mechanistic work demonstrated that DNA damage-induced apoptosis contributes to the cytotoxicity of dronedarone. In this study, we examined further the underlying mech...

詳細記述

保存先:
書誌詳細
出版年:Arch Toxicol
主要な著者: Chen, Si, Wu, Qiangen, Ning, Baitang, Bryant, Matthew, Guo, Lei
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348481/
https://ncbi.nlm.nih.gov/pubmed/29616291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-018-2196-x
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