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The role of hepatic cytochrome P450s in the cytotoxicity of dronedarone
Dronedarone is used to treat patients with cardiac arrhythmias and has been reported to be associated with liver injury. Our previous mechanistic work demonstrated that DNA damage-induced apoptosis contributes to the cytotoxicity of dronedarone. In this study, we examined further the underlying mech...
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| Published in: | Arch Toxicol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6348481/ https://ncbi.nlm.nih.gov/pubmed/29616291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-018-2196-x |
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