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Mechanisms of tolvaptan-induced toxicity in HepG2 cells()
Tolvaptan, a vasopressin receptor 2 antagonist used to treat hyponatremia, has recently been reported to be associated with an increased risk of liver injury. In this study, we explored the underlying mechanisms of hepatotoxicity of tolvaptan using human HepG2 cells. Tolvaptan inhibited cell growth...
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| Publicado no: | Biochem Pharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5894093/ https://ncbi.nlm.nih.gov/pubmed/25858412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.03.015 |
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