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Mechanisms of tolvaptan-induced toxicity in HepG2 cells()

Tolvaptan, a vasopressin receptor 2 antagonist used to treat hyponatremia, has recently been reported to be associated with an increased risk of liver injury. In this study, we explored the underlying mechanisms of hepatotoxicity of tolvaptan using human HepG2 cells. Tolvaptan inhibited cell growth...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biochem Pharmacol
Päätekijät: Wu, Yuanfeng, Beland, Frederick A., Chen, Si, Liu, Fang, Guo, Lei, Fang, Jia-Long
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894093/
https://ncbi.nlm.nih.gov/pubmed/25858412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.03.015
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