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PRDM9 and its role in genetic recombination
PRDM9 is a zinc finger protein that binds DNA at specific locations in the genome where it trimethylates histone H3 at lysines 4 and 36 at surrounding nucleosomes. In meiosis in many species, including humans and mice where PRDM9 has been most intensely studied, these actions determine the location...
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| Publicat a: | Trends Genet |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5878713/ https://ncbi.nlm.nih.gov/pubmed/29366606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2017.12.017 |
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