A Statistical Thermodynamic Model for Ligands Interacting With Ion Channels: Theoretical Model and Experimental Validation of the KCNQ2 Channel

Ion channels are important therapeutic targets, and their pharmacology is becoming increasingly important. However, knowledge of the mechanism of interaction of the activators and ion channels is still limited due to the complexity of the mechanisms. A statistical thermodynamic model has been develo...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Pharmacol
Main Authors: Bai, Fang, Pi, Xiaoping, Li, Ping, Zhou, Pingzheng, Yang, Huaiyu, Wang, Xicheng, Li, Min, Gao, Zhaobing, Jiang, Hualiang
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2018
נושאים:
Pharmacology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855359/
https://ncbi.nlm.nih.gov/pubmed/29593528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00150
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