A Theoretical Model for Calculating Voltage Sensitivity of Ion Channels and the Application on Kv1.2 Potassium Channel

Voltage sensing confers conversion of a change in membrane potential to signaling activities underlying the physiological processes. For an ion channel, voltage sensitivity is usually experimentally measured by fitting electrophysiological data to Boltzmann distributions. In our study, a two-state m...

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Hlavní autoři: Yang, Huaiyu, Gao, Zhaobing, Li, Ping, Yu, Kunqian, Yu, Ye, Xu, Tian-Le, Li, Min, Jiang, Hualiang
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2012
Témata:
Channels and Transporters
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328696/
https://ncbi.nlm.nih.gov/pubmed/22768937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.032
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