Calculation of the Gating Charge for the Kv1.2 Voltage-Activated Potassium Channel

The atomic models of the Kv1.2 potassium channel in the active and resting state, originally presented elsewhere, are here refined using molecular dynamics simulations in an explicit membrane-solvent environment. With a minor adjustment of the orientation of the first arginine along the S4 segment,...

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Autors principals: Khalili-Araghi, Fatemeh, Jogini, Vishwanath, Yarov-Yarovoy, Vladimir, Tajkhorshid, Emad, Roux, Benoît, Schulten, Klaus
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2010
Matèries:
Channels and Transporters
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872222/
https://ncbi.nlm.nih.gov/pubmed/20483327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.02.056
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