Calculation of the Gating Charge for the Kv1.2 Voltage-Activated Potassium Channel

The atomic models of the Kv1.2 potassium channel in the active and resting state, originally presented elsewhere, are here refined using molecular dynamics simulations in an explicit membrane-solvent environment. With a minor adjustment of the orientation of the first arginine along the S4 segment,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Khalili-Araghi, Fatemeh, Jogini, Vishwanath, Yarov-Yarovoy, Vladimir, Tajkhorshid, Emad, Roux, Benoît, Schulten, Klaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2010
Schlagworte:
Channels and Transporters
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872222/
https://ncbi.nlm.nih.gov/pubmed/20483327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.02.056
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