A Theoretical Model for Calculating Voltage Sensitivity of Ion Channels and the Application on Kv1.2 Potassium Channel

Voltage sensing confers conversion of a change in membrane potential to signaling activities underlying the physiological processes. For an ion channel, voltage sensitivity is usually experimentally measured by fitting electrophysiological data to Boltzmann distributions. In our study, a two-state m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Huaiyu, Gao, Zhaobing, Li, Ping, Yu, Kunqian, Yu, Ye, Xu, Tian-Le, Li, Min, Jiang, Hualiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2012
Schlagworte:
Channels and Transporters
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328696/
https://ncbi.nlm.nih.gov/pubmed/22768937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.032
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