A Theoretical Model for Calculating Voltage Sensitivity of Ion Channels and the Application on Kv1.2 Potassium Channel

Voltage sensing confers conversion of a change in membrane potential to signaling activities underlying the physiological processes. For an ion channel, voltage sensitivity is usually experimentally measured by fitting electrophysiological data to Boltzmann distributions. In our study, a two-state m...

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Bibliographic Details
Main Authors: Yang, Huaiyu, Gao, Zhaobing, Li, Ping, Yu, Kunqian, Yu, Ye, Xu, Tian-Le, Li, Min, Jiang, Hualiang
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2012
Subjects:
Channels and Transporters
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328696/
https://ncbi.nlm.nih.gov/pubmed/22768937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.032
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