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Molecular basis for ligand activation of the human KCNQ2 channel
The voltage-gated potassium channel KCNQ2 is responsible for M-current in neurons and is an important drug target to treat epilepsy, pain and several other diseases related to neuronal hyper-excitability. A list of synthetic compounds have been developed to directly activate KCNQ2, yet our knowledge...
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| Gepubliceerd in: | Cell Res |
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| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Springer Singapore
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7852908/ https://ncbi.nlm.nih.gov/pubmed/32884139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-020-00410-8 |
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