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New Molecular Insight into Mechanism of Evolution of Mammalian Synthetic Prions
Previous studies established that transmissible prion diseases could be induced by in vitro-produced recombinant prion protein (PrP) fibrils with structures that are fundamentally different from that of authentic PrP scrapie isoform (PrP(Sc)). To explain evolution of synthetic prions, a new mechanis...
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| Veröffentlicht in: | Am J Pathol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Investigative Pathology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5848243/ https://ncbi.nlm.nih.gov/pubmed/26873446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.11.013 |
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