Recombinant prion protein induces a new transmissible prion disease in wild-type animals

Prion disease is a neurodegenerative malady, which is believed to be transmitted via a prion protein in its abnormal conformation (PrP(Sc)). Previous studies have failed to demonstrate that prion disease could be induced in wild-type animals using recombinant prion protein (rPrP) produced in Escheri...

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Autori principali: Makarava, Natallia, Kovacs, Gabor G., Bocharova, Olga, Savtchenko, Regina, Alexeeva, Irina, Budka, Herbert, Rohwer, Robert G., Baskakov, Ilia V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2010
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808531/
https://ncbi.nlm.nih.gov/pubmed/20052481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-009-0633-x
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