Cohesin loss eliminates all loop domains

The human genome folds to create thousands of intervals, called “contact domains,” that exhibit enhanced contact frequency within themselves. “Loop domains” form because of tethering between two loci – almost always bound by CTCF and cohesin – lying on the same chromosome. “Compartment domains” form...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell
Päätekijät: Rao, Suhas S. P., Huang, Su-Chen, St Hilaire, Brian Glenn, Engreitz, Jesse M., Perez, Elizabeth M., Kieffer-Kwon, Kyong-Rim, Sanborn, Adrian L., Johnstone, Sarah E., Bascom, Gavin D., Bochkov, Ivan D., Huang, Xingfan, Shamim, Muhammad S., Shin, Jaeweon, Turner, Douglass, Ye, Ziyi, Omer, Arina D., Robinson, James T., Schlick, Tamar, Bernstein, Bradley E., Casellas, Rafael, Lander, Eric S., Aiden, Erez Lieberman
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846482/
https://ncbi.nlm.nih.gov/pubmed/28985562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.026
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