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Cohesin loss eliminates all loop domains
The human genome folds to create thousands of intervals, called “contact domains,” that exhibit enhanced contact frequency within themselves. “Loop domains” form because of tethering between two loci – almost always bound by CTCF and cohesin – lying on the same chromosome. “Compartment domains” form...
Tallennettuna:
| Julkaisussa: | Cell |
|---|---|
| Päätekijät: | , , , , , , , , , , , , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846482/ https://ncbi.nlm.nih.gov/pubmed/28985562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.026 |
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