Cohesin loss eliminates all loop domains

The human genome folds to create thousands of intervals, called “contact domains,” that exhibit enhanced contact frequency within themselves. “Loop domains” form because of tethering between two loci – almost always bound by CTCF and cohesin – lying on the same chromosome. “Compartment domains” form...

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Библиографические подробности
Опубликовано в: :Cell
Главные авторы: Rao, Suhas S. P., Huang, Su-Chen, St Hilaire, Brian Glenn, Engreitz, Jesse M., Perez, Elizabeth M., Kieffer-Kwon, Kyong-Rim, Sanborn, Adrian L., Johnstone, Sarah E., Bascom, Gavin D., Bochkov, Ivan D., Huang, Xingfan, Shamim, Muhammad S., Shin, Jaeweon, Turner, Douglass, Ye, Ziyi, Omer, Arina D., Robinson, James T., Schlick, Tamar, Bernstein, Bradley E., Casellas, Rafael, Lander, Eric S., Aiden, Erez Lieberman
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846482/
https://ncbi.nlm.nih.gov/pubmed/28985562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.026
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