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A three-dimensional map of the human genome at kilobase resolution reveals principles of chromatin looping
We use in situ Hi-C to probe the three-dimensional architecture of genomes, constructing haploid and diploid maps of nine cell types. The densest, in human lymphoblastoid cells, contains 4.9 billion contacts, achieving 1-kilobase resolution. We find that genomes are partitioned into local domains, w...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5635824/ https://ncbi.nlm.nih.gov/pubmed/25497547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.11.021 |
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