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Polycomb-mediated chromatin loops revealed by a subkilobase-resolution chromatin interaction map

The locations of chromatin loops in Drosophila were determined by Hi-C (chemical cross-linking, restriction digestion, ligation, and high-throughput DNA sequencing). Whereas most loop boundaries or “anchors” are associated with CTCF protein in mammals, loop anchors in Drosophila were found most ofte...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Eagen, Kyle P., Aiden, Erez Lieberman, Kornberg, Roger D.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565414/
https://ncbi.nlm.nih.gov/pubmed/28765367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701291114
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