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Chromatin Is Frequently Unknotted at the Megabase Scale

Knots in the human genome would greatly impact diverse cellular processes ranging from transcription to gene regulation. To date, it has not been possible to directly examine the genome in vivo for the presence of knots. Recently, methods for serial fluorescent in situ hybridization have made it pos...

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Bibliografische gegevens
Gepubliceerd in:Biophys J
Hoofdauteurs: Goundaroulis, Dimos, Lieberman Aiden, Erez, Stasiak, Andrzej
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202934/
https://ncbi.nlm.nih.gov/pubmed/31818464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.11.002
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