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Chromatin Is Frequently Unknotted at the Megabase Scale

Knots in the human genome would greatly impact diverse cellular processes ranging from transcription to gene regulation. To date, it has not been possible to directly examine the genome in vivo for the presence of knots. Recently, methods for serial fluorescent in situ hybridization have made it pos...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Goundaroulis, Dimos, Lieberman Aiden, Erez, Stasiak, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202934/
https://ncbi.nlm.nih.gov/pubmed/31818464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.11.002
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