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DNA supercoiling and its role in DNA decatenation and unknotting

Chromosomal and plasmid DNA molecules in bacterial cells are maintained under torsional tension and are therefore supercoiled. With the exception of extreme thermophiles, supercoiling has a negative sign, which means that the torsional tension diminishes the DNA helicity and facilitates strand separ...

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Detalhes bibliográficos
Main Authors: Witz, Guillaume, Stasiak, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853108/
https://ncbi.nlm.nih.gov/pubmed/20026582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1161
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