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The energetics and physiological impact of cohesin extrusion
Cohesin extrusion is thought to play a central role in establishing the architecture of mammalian genomes. However, extrusion has not been visualized in-vivo and thus its functional impact and energetics are unknown. Using ultra-deep Hi-C we show that loop domains form by a process that requires coh...
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| Vydáno v: | Cell |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6065110/ https://ncbi.nlm.nih.gov/pubmed/29706548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.03.072 |
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