Permanganate/S1 nuclease footprinting reveals non-B DNA structures with regulatory potential across a mammalian genome

DNA in cells is predominantly B-form double helix. Though certain DNA sequences in vitro may fold into other structures, such as triplex, left-handed Z-form, or quadruplex DNA, the stability and prevalence of these structures in vivo are not known. Here, using computational analysis of sequence moti...

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Detalhes bibliográficos
Publicado no:Cell Syst
Main Authors: Kouzine, Fedor, Wojtowicz, Damian, Baranello, Laura, Yamane, Arito, Nelson, Steevenson, Resch, Wolfgang, Kieffer-Kwon, Kyong-Rim, Benham, Craig, Casellas, Rafael, Przytycka, Teresa M., Levens, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7432990/
https://ncbi.nlm.nih.gov/pubmed/28237796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.01.013
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