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Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2
The Polycomb repressive complex 2 (PRC2) catalyzes H3K27 methylation and is required for maintaining transcriptional patterns and cellular identity, but the specification and maintenance of genomic PRC2 binding and H3K27 methylation patterns remain incompletely understood. Epigenetic mechanisms have...
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| Опубликовано в: : | Nat Struct Mol Biol |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5842896/ https://ncbi.nlm.nih.gov/pubmed/29483650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0036-6 |
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