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Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer

The chromatin environment is modulated by a machinery of chromatin modifiers, required for the specification and maintenance of cell fate. Many mutations in the machinery have been linked to the development and progression of cancer. In this review, we give a brief introduction to Polycomb group (Pc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cold Spring Harb Perspect Med
Egile Nagusiak: Laugesen, Anne, Højfeldt, Jonas Westergaard, Helin, Kristian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008062/
https://ncbi.nlm.nih.gov/pubmed/27449971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026575
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