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Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer

The chromatin environment is modulated by a machinery of chromatin modifiers, required for the specification and maintenance of cell fate. Many mutations in the machinery have been linked to the development and progression of cancer. In this review, we give a brief introduction to Polycomb group (Pc...

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Bibliografische gegevens
Gepubliceerd in:Cold Spring Harb Perspect Med
Hoofdauteurs: Laugesen, Anne, Højfeldt, Jonas Westergaard, Helin, Kristian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008062/
https://ncbi.nlm.nih.gov/pubmed/27449971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026575
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