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Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer

The chromatin environment is modulated by a machinery of chromatin modifiers, required for the specification and maintenance of cell fate. Many mutations in the machinery have been linked to the development and progression of cancer. In this review, we give a brief introduction to Polycomb group (Pc...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Laugesen, Anne, Højfeldt, Jonas Westergaard, Helin, Kristian
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008062/
https://ncbi.nlm.nih.gov/pubmed/27449971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026575
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