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Molecular mechanisms directing PRC2 recruitment and H3K27 methylation

The Polycomb Repressive Complex 2 (PRC2) is a chromatin-associated methyltransferase catalyzing mono-, di- and trimethylation of lysine 27 on histone H3 (H3K27). This activity is required for normal organismal development and maintenance of gene expression patterns to uphold cell identity. PRC2 func...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell
Prif Awduron: Laugesen, Anne, Højfeldt, Jonas Westergaard, Helin, Kristian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452890/
https://ncbi.nlm.nih.gov/pubmed/30951652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.03.011
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