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Molecular mechanisms directing PRC2 recruitment and H3K27 methylation
The Polycomb Repressive Complex 2 (PRC2) is a chromatin-associated methyltransferase catalyzing mono-, di- and trimethylation of lysine 27 on histone H3 (H3K27). This activity is required for normal organismal development and maintenance of gene expression patterns to uphold cell identity. PRC2 func...
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| Pubblicato in: | Mol Cell |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6452890/ https://ncbi.nlm.nih.gov/pubmed/30951652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.03.011 |
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