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H3K36 Methylation Antagonizes PRC2-mediated H3K27 Methylation
H3K27 methylation mediated by the histone methyltransferase complex PRC2 is critical for transcriptional regulation, Polycomb silencing, Drosophila segmentation, mammalian X chromosome inactivation, and cancer. PRC2-mediated H3K27 methylation can spread along the chromatin and propagate the repressi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048685/ https://ncbi.nlm.nih.gov/pubmed/21239496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.194027 |
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