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Non-core subunits of the PRC2 complex are collectively required for its target site specificity

The Polycomb repressive complex 2 (PRC2) catalyzes H3K27 methylation across the genome, which impacts transcriptional regulation and is critical for establishment of cell identity. Because of its essential function during development and in cancer, understanding the delineation of genome-wide H3K27...

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Dettagli Bibliografici
Pubblicato in:Mol Cell
Autori principali: Westergaard Højfeldt, Jonas, Hedehus, Lin, Laugesen, Anne, Tatar, Tülin, Wiehle, Laura, Helin, Kristian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842426/
https://ncbi.nlm.nih.gov/pubmed/31521506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.031
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