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Utx Is Required for Proper Induction of Ectoderm and Mesoderm during Differentiation of Embryonic Stem Cells

Embryonic development requires chromatin remodeling for dynamic regulation of gene expression patterns to ensure silencing of pluripotent transcription factors and activation of developmental regulators. Demethylation of H3K27me3 by the histone demethylases Utx and Jmjd3 is important for the activat...

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Библиографические подробности
Главные авторы: Morales Torres, Cristina, Laugesen, Anne, Helin, Kristian
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616089/
https://ncbi.nlm.nih.gov/pubmed/23573229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060020
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