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Utx Is Required for Proper Induction of Ectoderm and Mesoderm during Differentiation of Embryonic Stem Cells

Embryonic development requires chromatin remodeling for dynamic regulation of gene expression patterns to ensure silencing of pluripotent transcription factors and activation of developmental regulators. Demethylation of H3K27me3 by the histone demethylases Utx and Jmjd3 is important for the activat...

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Autori principali: Morales Torres, Cristina, Laugesen, Anne, Helin, Kristian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616089/
https://ncbi.nlm.nih.gov/pubmed/23573229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060020
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