Prostaglandin E(2) Is Required for BMP4-Induced Mesoderm Differentiation of Human Embryonic Stem Cells

The accurate control of early cell fate specification during differentiation of human embryonic stem cells (hESCs) is critical for acquiring pure therapeutic cell populations of interest. Bone morphogenetic protein 4 (BMP4) is a key mesoderm inducer from ESCs. However, the molecular mechanism of the...

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Pubblicato in:Stem Cell Reports
Autori principali: Zhang, Bowen, He, Lijuan, Liu, Yiming, Zhang, Jing, Zeng, Quan, Wang, Sihan, Fan, Zeng, Fang, Fang, Chen, Lin, Lv, Yang, Xi, Jiafei, Yue, Wen, Li, Yanhua, Pei, Xuetao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919771/
https://ncbi.nlm.nih.gov/pubmed/29478896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.01.024
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