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Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis

Bone morphogenetic proteins (Bmps) are members of the transforming growth factor β (TGFβ) superfamily that play critical roles during mouse embryogenesis. Signaling by Bmp receptors is mediated mainly by Smad proteins. In this study, we show that a targeted null mutation of Ecsit, encoding a signali...

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Detalhes bibliográficos
Main Authors: Xiao, Changchun, Shim, Jae-hyuck, Klüppel, Michael, Zhang, Samuel Shao-Min, Dong, Chen, Flavell, Richard A., Fu, Xin-Yuan, Wrana, Jeffrey L., Hogan, Brigid L.M., Ghosh, Sankar
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC289152/
https://ncbi.nlm.nih.gov/pubmed/14633973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1145603
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