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Non-core subunits of the PRC2 complex are collectively required for its target site specificity
The Polycomb repressive complex 2 (PRC2) catalyzes H3K27 methylation across the genome, which impacts transcriptional regulation and is critical for establishment of cell identity. Because of its essential function during development and in cancer, understanding the delineation of genome-wide H3K27...
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| Publicado en: | Mol Cell |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6842426/ https://ncbi.nlm.nih.gov/pubmed/31521506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.031 |
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