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Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
SUZ12 is a recently identified Polycomb group (PcG) protein, which together with EZH2 and EED forms different Polycomb repressive complexes (PRC2/3). These complexes contain histone H3 lysine (K) 27/9 and histone H1 K26 methyltransferase activity specified by the EZH2 SET domain. Here we show that m...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524339/ https://ncbi.nlm.nih.gov/pubmed/15385962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600402 |
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