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Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

SUZ12 is a recently identified Polycomb group (PcG) protein, which together with EZH2 and EED forms different Polycomb repressive complexes (PRC2/3). These complexes contain histone H3 lysine (K) 27/9 and histone H1 K26 methyltransferase activity specified by the EZH2 SET domain. Here we show that m...

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Detalhes bibliográficos
Main Authors: Pasini, Diego, Bracken, Adrian P, Jensen, Michael R, Denchi, Eros Lazzerini, Helin, Kristian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC524339/
https://ncbi.nlm.nih.gov/pubmed/15385962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600402
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