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Effects of rigidity on the selectivity of protein kinase inhibitors
Established strategies for discovering selective kinase inhibitors are target-centric as they often target certain structural or reactive features in the target kinase. In the absence of such prominent features, there is a lack of general methods for discovering selective inhibitors. Here we describ...
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| Publicat a: | Eur J Med Chem |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5816697/ https://ncbi.nlm.nih.gov/pubmed/29407977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2018.01.053 |
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