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Measuring and interpreting the selectivity of protein kinase inhibitors
Protein kinase inhibitors are a well-established class of clinically useful drugs, particularly for the treatment of cancer. Achieving inhibitor selectivity for particular protein kinases often remains a significant challenge in the development of new small molecules as drugs or as tools for chemica...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2725273/ https://ncbi.nlm.nih.gov/pubmed/19568781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-009-0023-9 |
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