Myelosuppression and kinase selectivity of multikinase angiogenesis inhibitors

BACKGROUND: Myelosuppression has been observed with several multikinase angiogenesis inhibitors in clinical studies, although the frequency and severity varies among the different agents. Inhibitors targeting vascular endothelial growth factor receptor (VEGFR) often inhibit other kinases, which may...

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Detalles Bibliográficos
Autores principales: Kumar, R, Crouthamel, M-C, Rominger, D H, Gontarek, R R, Tummino, P J, Levin, R A, King, A G
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2009
Materias:
Molecular Diagnostics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768111/
https://ncbi.nlm.nih.gov/pubmed/19844230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605366
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