Myelosuppression and kinase selectivity of multikinase angiogenesis inhibitors

BACKGROUND: Myelosuppression has been observed with several multikinase angiogenesis inhibitors in clinical studies, although the frequency and severity varies among the different agents. Inhibitors targeting vascular endothelial growth factor receptor (VEGFR) often inhibit other kinases, which may...

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Main Authors: Kumar, R, Crouthamel, M-C, Rominger, D H, Gontarek, R R, Tummino, P J, Levin, R A, King, A G
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2009
主題:
Molecular Diagnostics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768111/
https://ncbi.nlm.nih.gov/pubmed/19844230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605366
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