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Traceless Silylation of β-C(sp(3))–H Bonds of Alcohols via Perfluorinated Acetals

We report the silylation of primary C–H bonds located β to secondary and tertiary alcohols by exploiting perfluorinated esters as traceless directing groups. The conversion of a secondary or tertiary alcohol to a perfluoroalkyl ester and conversion of the ester to the corresponding silyl acetals by...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Bunescu, Ala, Butcher, Trevor W., Hartwig, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809123/
https://ncbi.nlm.nih.gov/pubmed/29283571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b12150
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