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Metabolic Profiling of CB1 Neutral Antagonists
PIMSR is among the first neutral antagonists for the CB1R and was demonstrated pharmacologically to bind to the CB1R, yet not alter calcium flux. It was further shown computationally to be able to stabilize both the active and inactive states of CB1R revealing the molecular interactions that mechani...
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| Publicado no: | Methods Enzymol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5802864/ https://ncbi.nlm.nih.gov/pubmed/28750803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.06.025 |
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