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Diphenyl Purine Derivatives as Peripherally Selective Cannabinoid Receptor 1 Antagonists
Cannabinoid receptor 1 (CB1) antagonists are potentially useful for the treatment of several diseases. However, clinical development of several CB1 antagonists was halted due to central nervous system (CNS)-related side effects including depression and suicidal ideation in some users. Recently, stud...
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| Veröffentlicht in: | J Med Chem |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4492447/ https://ncbi.nlm.nih.gov/pubmed/23098108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301181r |
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