Histone demethylase LSD1 regulates hematopoietic stem cells homeostasis and protects from death by endotoxic shock

Hematopoietic stem cells (HSCs) maintain a quiescent state during homeostasis, but with acute infection, they exit the quiescent state to increase the output of immune cells, the so-called “emergency hematopoiesis.” However, HSCs’ response to severe infection during septic shock and the pathological...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Wang, Jianxun, Saijo, Kaoru, Skola, Dylan, Jin, Chunyu, Ma, Qi, Merkurjev, Daria, Glass, Christopher K., Rosenfeld, Michael G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2018
Gaiak:
PNAS Plus
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777077/
https://ncbi.nlm.nih.gov/pubmed/29263096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718759114
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