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Histone demethylase LSD1 regulates hematopoietic stem cells homeostasis and protects from death by endotoxic shock
Hematopoietic stem cells (HSCs) maintain a quiescent state during homeostasis, but with acute infection, they exit the quiescent state to increase the output of immune cells, the so-called “emergency hematopoiesis.” However, HSCs’ response to severe infection during septic shock and the pathological...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5777077/ https://ncbi.nlm.nih.gov/pubmed/29263096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718759114 |
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